Einstein Image

Einstein Image

Error: No layouts found

2016-einstein-img

Einstein Image

Joining the circulatory systems of an old and a young animal is called heterochronic parabiosis. Here we see a cross-section of the small intestine of a young mouse that was parabiosed to an old mouse for two months. Postdoctoral research fellow Tahmineh Tabrizian, M.D., Ph.D., has found that factors in old-mouse blood “age” intestinal stem cells in young mice by impairing their ability to proliferate. (The stem-cell damage can’t be seen in this low-magnification image.) The next step in Dr. Tabrizian’s research: Identify the stem-cell aging factors present in old blood and see whether targeting those factors (using neutralizing antibodies, for example) helps rejuvenate stem cells in old mice and, ultimately, in old people. Dr. Tabrizian’s mentor is Derek M. Huffman, Ph.D., an assistant professor of molecular pharmacology and of medicine (endocrinology).

The Issue at a Glance

More From Einstein

Preparing New Grads for Hospital Roles
Einstein Celebrates 65th Commencement
Class of 2027 Receives White Coats
Mentoring in Medicine Paves Way for Success
Biomedical Sciences Leadership Program Begins
Einstein, Lehman Launch M.S. Program
2023 National Diversity Award
Health Equity Scholarship Honors Nilda Soto
Longevity Gene Project Awarded $13.6M

Content

Highlights
Features
Campus News
Research Notes
Motivations: Donors & Alumni
More From This Issue

Past Issues

Download Magazine

Search

Subscribe

  • This field is for validation purposes and should be left unchanged.